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3kbx
From Proteopedia
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==Human macrophage inflammatory protein-1 alpha L3M_V63M== | ==Human macrophage inflammatory protein-1 alpha L3M_V63M== | ||
| - | <StructureSection load='3kbx' size='340' side='right' caption='[[3kbx]], [[Resolution|resolution]] 2.65Å' scene=''> | + | <StructureSection load='3kbx' size='340' side='right'caption='[[3kbx]], [[Resolution|resolution]] 2.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3kbx]] is a 5 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3kbx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KBX FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.652Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kbx OCA], [https://pdbe.org/3kbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kbx RCSB], [https://www.ebi.ac.uk/pdbsum/3kbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kbx ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CCL3_HUMAN CCL3_HUMAN] Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).<ref>PMID:8525373</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Guo | + | [[Category: Large Structures]] |
| - | [[Category: Ren | + | [[Category: Guo Q]] |
| - | [[Category: Tang | + | [[Category: Ren M]] |
| - | + | [[Category: Tang W-J]] | |
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Current revision
Human macrophage inflammatory protein-1 alpha L3M_V63M
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Categories: Homo sapiens | Large Structures | Guo Q | Ren M | Tang W-J
