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4ogl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==X-ray structure uridine phosphorylase from Vibrio cholerae in complex with thymine at 1.25 A resolution== | |
| + | <StructureSection load='4ogl' size='340' side='right'caption='[[4ogl]], [[Resolution|resolution]] 1.25Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ogl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OGL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.249Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TDR:THYMINE'>TDR</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ogl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogl OCA], [https://pdbe.org/4ogl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ogl RCSB], [https://www.ebi.ac.uk/pdbsum/4ogl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ogl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9KT71_VIBCH Q9KT71_VIBCH] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.[RuleBase:RU361131] | ||
| - | + | ==See Also== | |
| - | + | *[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Betzel | + | [[Category: Vibrio cholerae O1 biovar El Tor str. N16961]] |
| - | [[Category: | + | [[Category: Betzel C]] |
| - | [[Category: Lashkov | + | [[Category: Gabdoulkhakov AG]] |
| - | [[Category: | + | [[Category: Lashkov AA]] |
| + | [[Category: Mikhailov AM]] | ||
| + | [[Category: Prokofev II]] | ||
Current revision
X-ray structure uridine phosphorylase from Vibrio cholerae in complex with thymine at 1.25 A resolution
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