4opn
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of mouse glyoxalase I complexed with mAH== | |
| + | <StructureSection load='4opn' size='340' side='right'caption='[[4opn]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4opn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OPN FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZBF:L-GAMMA-GLUTAMYL-N-(3-ETHYNYLPHENYL)-N-HYDROXY-L-GLUTAMINYLGLYCINE'>ZBF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4opn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4opn OCA], [https://pdbe.org/4opn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4opn RCSB], [https://www.ebi.ac.uk/pdbsum/4opn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4opn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LGUL_MOUSE LGUL_MOUSE] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Glyoxalase 3D structures|Glyoxalase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Yuan M]] |
| - | [[Category: | + | [[Category: Zhai J]] |
| + | [[Category: Zhang H]] | ||
| + | [[Category: Zhang L]] | ||
Current revision
Crystal structure of mouse glyoxalase I complexed with mAH
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Categories: Large Structures | Mus musculus | Yuan M | Zhai J | Zhang H | Zhang L
