1xgw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:45, 23 August 2023) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1xgw.gif|left|200px]]
 
-
{{Structure
+
==The crystal structure of human enthoprotin N-terminal domain==
-
|PDB= 1xgw |SIZE=350|CAPTION= <scene name='initialview01'>1xgw</scene>, resolution 1.90&Aring;
+
<StructureSection load='1xgw' size='340' side='right'caption='[[1xgw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[1xgw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XGW FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
|GENE= EPN4, EPNR, ENTH, KIAA0171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xgw OCA], [https://pdbe.org/1xgw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xgw RCSB], [https://www.ebi.ac.uk/pdbsum/1xgw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xgw ProSAT]</span></td></tr>
-
}}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/EPN4_HUMAN EPN4_HUMAN] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.<ref>PMID:12429846</ref> <ref>PMID:12538641</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xg/1xgw_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xgw ConSurf].
 +
<div style="clear:both"></div>
-
'''The crystal structure of human enthoprotin N-terminal domain'''
+
==See Also==
-
 
+
*[[Epsin|Epsin]]
-
 
+
== References ==
-
==Disease==
+
<references/>
-
Known diseases associated with this structure: Schizophrenia, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607265 607265]]
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
-
1XGW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA].
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Cygler, M.]]
+
[[Category: Cygler M]]
-
[[Category: Lunin, V V.]]
+
[[Category: Lunin VV]]
-
[[Category: Mazzoni, I.]]
+
[[Category: Mazzoni I]]
-
[[Category: Munger, C.]]
+
[[Category: Munger C]]
-
[[Category: Wagner, J.]]
+
[[Category: Wagner J]]
-
[[Category: clathrin-associated]]
+
-
[[Category: enth]]
+
-
[[Category: enthoprotin]]
+
-
[[Category: epsin-related]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:09:40 2008''
+

Current revision

The crystal structure of human enthoprotin N-terminal domain

PDB ID 1xgw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xgw"
Personal tools