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2lo9
From Proteopedia
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==NMR solution structure of Mu-contoxin BuIIIB== | ==NMR solution structure of Mu-contoxin BuIIIB== | ||
| - | <StructureSection load='2lo9' size='340' side='right' caption='[[2lo9 | + | <StructureSection load='2lo9' size='340' side='right'caption='[[2lo9]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lo9]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LO9 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[2lo9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_bullatus Conus bullatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LO9 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lo9 OCA], [https://pdbe.org/2lo9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lo9 RCSB], [https://www.ebi.ac.uk/pdbsum/2lo9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lo9 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CM3B_CONBU CM3B_CONBU] Mu-conotoxins block voltage-gated sodium channels. Extremely potent inhibitor of Nav1.4/SCN4A. The inhibition is very slowly reversible. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2lo9" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Conus bullatus]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Kuang Z]] | ||
Current revision
NMR solution structure of Mu-contoxin BuIIIB
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