1xl9

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[[Image:1xl9.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis.==
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|PDB= 1xl9 |SIZE=350|CAPTION= <scene name='initialview01'>1xl9</scene>, resolution 2.23&Aring;
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<StructureSection load='1xl9' size='340' side='right'caption='[[1xl9]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1xl9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XL9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XL9 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrodipicolinate_synthase Dihydrodipicolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.52 4.2.1.52]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.23&#8491;</td></tr>
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|GENE= DapA-2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xl9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xl9 OCA], [https://pdbe.org/1xl9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xl9 RCSB], [https://www.ebi.ac.uk/pdbsum/1xl9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xl9 ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A6L7H340_BACAN A0A6L7H340_BACAN] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[ARBA:ARBA00003294][HAMAP-Rule:MF_00418]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xl/1xl9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xl9 ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis.'''
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==See Also==
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*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1XL9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XL9 OCA].
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==Reference==
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Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution., Blagova E, Levdikov V, Milioti N, Fogg MJ, Kalliomaa AK, Brannigan JA, Wilson KS, Wilkinson AJ, Proteins. 2006 Jan 1;62(1):297-301. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16287120 16287120]
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[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Dihydrodipicolinate synthase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Blagova E]]
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[[Category: Blagova, E.]]
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[[Category: Brannigan JA]]
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[[Category: Brannigan, J A.]]
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[[Category: Fogg MJ]]
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[[Category: Fogg, M J.]]
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[[Category: Kalliomaa AK]]
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[[Category: Kalliomaa, A K.]]
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[[Category: Levdikov V]]
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[[Category: Levdikov, V.]]
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[[Category: Milioti N]]
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[[Category: Milioti, N.]]
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[[Category: Wilkinson AJ]]
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[[Category: Wilkinson, A J.]]
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[[Category: Wilson KS]]
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[[Category: Wilson, K S.]]
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[[Category: dihydrodipicolinate synthase; tim barrel; crystal structure; lysine biosynthesis; spine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:11:18 2008''
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Current revision

Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis.

PDB ID 1xl9

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