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2ebk

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==Solution structure of the RWD domain of human RWD domain containing protein 3==
==Solution structure of the RWD domain of human RWD domain containing protein 3==
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<StructureSection load='2ebk' size='340' side='right' caption='[[2ebk]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2ebk' size='340' side='right'caption='[[2ebk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ebk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EBK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ebk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBK FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RWDD3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ebk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ebk RCSB], [http://www.ebi.ac.uk/pdbsum/2ebk PDBsum], [http://www.topsan.org/Proteins/RSGI/2ebk TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebk OCA], [https://pdbe.org/2ebk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebk RCSB], [https://www.ebi.ac.uk/pdbsum/2ebk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebk ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebk TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RWDD3_HUMAN RWDD3_HUMAN]] Enhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination.<ref>PMID:17956732</ref>
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[https://www.uniprot.org/uniprot/RWDD3_HUMAN RWDD3_HUMAN] Enhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination.<ref>PMID:17956732</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebk_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebk_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ebk ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Harada, T]]
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[[Category: Large Structures]]
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[[Category: Kigawa, T]]
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[[Category: Harada T]]
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[[Category: Koshiba, S]]
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[[Category: Kigawa T]]
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[[Category: Structural genomic]]
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[[Category: Koshiba S]]
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[[Category: Watabe, S]]
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[[Category: Watabe S]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Yoneyama, M]]
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[[Category: Yoneyama M]]
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[[Category: Alpha+beta sandwich fold]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Rwd domain]]
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[[Category: Unknown function]]
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Current revision

Solution structure of the RWD domain of human RWD domain containing protein 3

PDB ID 2ebk

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