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3par

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==Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) in the absence of ligand==
==Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) in the absence of ligand==
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<StructureSection load='3par' size='340' side='right' caption='[[3par]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3par' size='340' side='right'caption='[[3par]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3par]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PAR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PAR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3par]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PAR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PAR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r13|1r13]], [[1r14|1r14]], [[3pak|3pak]], [[3paq|3paq]], [[3pbf|3pbf]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Sftp-1, Sftp1, Sftpa, Sftpa1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3par FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3par OCA], [https://pdbe.org/3par PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3par RCSB], [https://www.ebi.ac.uk/pdbsum/3par PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3par ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3par FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3par OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3par RCSB], [http://www.ebi.ac.uk/pdbsum/3par PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
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[https://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3par" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Cafarella, T M]]
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[[Category: Cafarella TM]]
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[[Category: Head, J]]
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[[Category: Head J]]
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[[Category: McCormack, F X]]
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[[Category: McCormack FX]]
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[[Category: Rynkiewicz, M J]]
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[[Category: Rynkiewicz MJ]]
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[[Category: Seaton, B A]]
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[[Category: Seaton BA]]
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[[Category: Shang, F]]
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[[Category: Shang F]]
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[[Category: Wu, H]]
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[[Category: Wu H]]
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[[Category: Carbohydrate binding]]
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[[Category: Collectin]]
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[[Category: Lectin]]
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[[Category: Mannose]]
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[[Category: Sugar binding protein]]
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Current revision

Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) in the absence of ligand

PDB ID 3par

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