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3wg8

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==Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist AS6==
==Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist AS6==
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<StructureSection load='3wg8' size='340' side='right' caption='[[3wg8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='3wg8' size='340' side='right'caption='[[3wg8]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wg8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WG8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3wg8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WG8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AS:(2Z,4E)-5-[(1S)-3-(HEXYLSULFANYL)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>6AS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wg8 RCSB], [http://www.ebi.ac.uk/pdbsum/3wg8 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6AS:(2Z,4E)-5-[(1S)-3-(HEXYLSULFANYL)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>6AS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg8 OCA], [https://pdbe.org/3wg8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wg8 RCSB], [https://www.ebi.ac.uk/pdbsum/3wg8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wg8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PYR1_ARATH PYR1_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19624469</ref> <ref>PMID:19407142</ref> <ref>PMID:19769575</ref>
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[https://www.uniprot.org/uniprot/PYR1_ARATH PYR1_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19624469</ref> <ref>PMID:19407142</ref> <ref>PMID:19769575</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3wg8" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Abscisic acid receptor 3D structures|Abscisic acid receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Akiyama, T]]
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[[Category: Arabidopsis thaliana]]
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[[Category: Cutler, S R]]
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[[Category: Large Structures]]
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[[Category: Endo, A]]
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[[Category: Akiyama T]]
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[[Category: Hirai, N]]
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[[Category: Cutler SR]]
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[[Category: Muto, T]]
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[[Category: Endo A]]
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[[Category: Nambara, E]]
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[[Category: Hirai N]]
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[[Category: Ohnishi, T]]
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[[Category: Muto T]]
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[[Category: Okamoto, M]]
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[[Category: Nambara E]]
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[[Category: Sue, M]]
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[[Category: Ohnishi T]]
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[[Category: Takeuchi, J]]
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[[Category: Okamoto M]]
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[[Category: Todoroki, Y]]
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[[Category: Sue M]]
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[[Category: Yajima, S]]
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[[Category: Takeuchi J]]
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[[Category: Abscisic acid]]
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[[Category: Todoroki Y]]
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[[Category: Hormone receptor]]
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[[Category: Yajima S]]

Current revision

Crystal structure of the abscisic acid receptor PYR1 in complex with an antagonist AS6

PDB ID 3wg8

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