4roe
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter== | |
+ | <StructureSection load='4roe' size='340' side='right'caption='[[4roe]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[4roe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ROE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ROE FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4roe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4roe OCA], [https://pdbe.org/4roe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4roe RCSB], [https://www.ebi.ac.uk/pdbsum/4roe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4roe ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/BRF2_HUMAN BRF2_HUMAN] General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites.<ref>PMID:11040218</ref> <ref>PMID:11121026</ref> <ref>PMID:11564744</ref> | ||
- | + | ==See Also== | |
- | + | *[[TATA-binding protein 3D structures|TATA-binding protein 3D structures]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: Guthertz | + | [[Category: Homo sapiens]] |
- | [[Category: Satia | + | [[Category: Large Structures]] |
+ | [[Category: Synthetic construct]] | ||
+ | [[Category: Gouge J]] | ||
+ | [[Category: Guthertz N]] | ||
+ | [[Category: Satia K]] | ||
+ | [[Category: Vannini A]] |
Current revision
Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter
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