2krc

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==Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase==
==Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase==
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<StructureSection load='2krc' size='340' side='right' caption='[[2krc]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2krc' size='340' side='right'caption='[[2krc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2krc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KRC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2krc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRC FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2krc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2krc RCSB], [http://www.ebi.ac.uk/pdbsum/2krc PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krc OCA], [https://pdbe.org/2krc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krc RCSB], [https://www.ebi.ac.uk/pdbsum/2krc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RPOE_BACSU RPOE_BACSU]] Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling. May function in sigma factor switching. It displaces RNA bound to RNA polymerase in a binary complex.
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[https://www.uniprot.org/uniprot/RPOE_BACSU RPOE_BACSU] Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling. May function in sigma factor switching. It displaces RNA bound to RNA polymerase in a binary complex.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krc_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2krc_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2krc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Jonak, J]]
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[[Category: Large Structures]]
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[[Category: Krasny, L]]
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[[Category: Jonak J]]
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[[Category: Motackova, V]]
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[[Category: Krasny L]]
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[[Category: Novacek, J]]
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[[Category: Motackova V]]
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[[Category: Padrta, P]]
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[[Category: Novacek J]]
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[[Category: Sanderova, H]]
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[[Category: Padrta P]]
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[[Category: Sklenar, V]]
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[[Category: Sanderova H]]
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[[Category: Svenkova, A]]
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[[Category: Sklenar V]]
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[[Category: Zidek, L]]
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[[Category: Svenkova A]]
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[[Category: Delta subunit]]
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[[Category: Zidek L]]
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[[Category: Dna-directed rna polymerase]]
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[[Category: Gram-positive bacteria]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Rna polymerase]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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Current revision

Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase

PDB ID 2krc

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