2jsi

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==11-23 obestatin fragment in DPC/SDS micellar solution==
==11-23 obestatin fragment in DPC/SDS micellar solution==
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<StructureSection load='2jsi' size='340' side='right' caption='[[2jsi]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
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<StructureSection load='2jsi' size='340' side='right'caption='[[2jsi]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jsi]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JSI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jsi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JSI FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 25 models</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jsj|2jsj]], [[2jsh|2jsh]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jsi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jsi RCSB], [http://www.ebi.ac.uk/pdbsum/2jsi PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jsi OCA], [https://pdbe.org/2jsi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jsi RCSB], [https://www.ebi.ac.uk/pdbsum/2jsi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jsi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GHRL_MOUSE GHRL_MOUSE]] Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
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[https://www.uniprot.org/uniprot/GHRL_MOUSE GHRL_MOUSE] Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2jsi" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Campiglia, P]]
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[[Category: Large Structures]]
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[[Category: Esposito, C]]
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[[Category: Mus musculus]]
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[[Category: Scrima, M]]
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[[Category: Campiglia P]]
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[[Category: Ursi, A M.D]]
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[[Category: D'Ursi AM]]
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[[Category: 11-23 obestatin fragment]]
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[[Category: Esposito C]]
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[[Category: Amidation]]
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[[Category: Scrima M]]
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[[Category: Dpc]]
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[[Category: Hormone]]
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[[Category: Lipoprotein]]
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[[Category: Micellar solution]]
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[[Category: Sd]]
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[[Category: Secreted]]
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11-23 obestatin fragment in DPC/SDS micellar solution

PDB ID 2jsi

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