4u6c
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==HsMetAP in complex with [(1R)-1-amino-3-cyclopentylpropyl]phosphonic acid== | |
| + | <StructureSection load='4u6c' size='340' side='right'caption='[[4u6c]], [[Resolution|resolution]] 1.91Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4u6c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U6C FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=Q06:[(1R)-1-AMINO-3-CYCLOPENTYLPROPYL]PHOSPHONIC+ACID'>Q06</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u6c OCA], [https://pdbe.org/4u6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u6c RCSB], [https://www.ebi.ac.uk/pdbsum/4u6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u6c ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MAP11_HUMAN MAP11_HUMAN] Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle.[HAMAP-Rule:MF_03174]<ref>PMID:16274222</ref> <ref>PMID:17114291</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Addlagatta | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Addlagatta A]] | ||
| + | [[Category: Arya T]] | ||
Current revision
HsMetAP in complex with [(1R)-1-amino-3-cyclopentylpropyl]phosphonic acid
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