1ys6

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[[Image:1ys6.gif|left|200px]]
 
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{{Structure
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==Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis==
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|PDB= 1ys6 |SIZE=350|CAPTION= <scene name='initialview01'>1ys6</scene>, resolution 1.77&Aring;
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<StructureSection load='1ys6' size='340' side='right'caption='[[1ys6]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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<table><tr><td colspan='2'>[[1ys6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YS6 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ys6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ys6 OCA], [https://pdbe.org/1ys6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ys6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ys6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ys6 ProSAT], [https://www.topsan.org/Proteins/XMTB/1ys6 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRRA_MYCTU PRRA_MYCTU] Member of the two-component regulatory system PrrB/PrrA. Involved specifically in early intracellular multiplication of Mycobacterium.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ys/1ys6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ys6 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis'''
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==See Also==
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*[[Response regulator 3D structure|Response regulator 3D structure]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1YS6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YS6 OCA].
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Single protein]]
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[[Category: Nowak E]]
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[[Category: Nowak, E.]]
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[[Category: Panjikar S]]
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[[Category: Panjikar, S.]]
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[[Category: Tucker P]]
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[[Category: Tucker, P.]]
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[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
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[[Category: CA]]
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[[Category: GOL]]
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[[Category: dna binding domain]]
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[[Category: mycobacterium tuberculosis structural proteomics project]]
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[[Category: response regulator protein]]
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[[Category: structural genomic]]
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[[Category: xmtb]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:26:49 2008''
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Current revision

Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis

PDB ID 1ys6

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