2ybr
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2ybr' size='340' side='right' caption='[[2ybr]], [[Resolution|resolution]] 2.55Å' scene=''> | + | ==Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann== |
| + | <StructureSection load='2ybr' size='340' side='right'caption='[[2ybr]], [[Resolution|resolution]] 2.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2ybr]] is a 9 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2ybr]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Centruroides_noxius Centruroides noxius] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YBR FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ybr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ybr OCA], [https://pdbe.org/2ybr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ybr RCSB], [https://www.ebi.ac.uk/pdbsum/2ybr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ybr ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/SCX2_CENNO SCX2_CENNO] Mammal beta-toxins bind voltage-independently at site-4 of sodium channels and shift the activation voltage to more negative potentials. This toxin is active against mammals. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2ybr" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Antibody 3D structures|Antibody 3D structures]] |
| + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
| + | *[[3D structures of human antibody|3D structures of human antibody]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Centruroides noxius]] | [[Category: Centruroides noxius]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Becerril | + | [[Category: Large Structures]] |
| - | [[Category: Canul-Tec | + | [[Category: Becerril B]] |
| - | [[Category: Possani | + | [[Category: Canul-Tec JC]] |
| - | [[Category: Riano-Umbarila | + | [[Category: Possani LD]] |
| - | [[Category: Rudino-Pinera | + | [[Category: Riano-Umbarila L]] |
| - | [[Category: Torres-Larios | + | [[Category: Rudino-Pinera E]] |
| - | + | [[Category: Torres-Larios A]] | |
| - | + | ||
Current revision
Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann
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