2w2s

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==STRUCTURE OF THE LAGOS BAT VIRUS MATRIX PROTEIN==
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<StructureSection load='2w2s' size='340' side='right' caption='[[2w2s]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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==Structure of the Lagos bat virus matrix protein==
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<StructureSection load='2w2s' size='340' side='right'caption='[[2w2s]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w2s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lagos_bat_virus Lagos bat virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W2S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w2s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lagos_bat_lyssavirus Lagos bat lyssavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W2S FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w2r|2w2r]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w2s RCSB], [http://www.ebi.ac.uk/pdbsum/2w2s PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w2s OCA], [https://pdbe.org/2w2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w2s RCSB], [https://www.ebi.ac.uk/pdbsum/2w2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w2s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MATRX_LBV MATRX_LBV]] Plays a major role in assembly and budding of virion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons (By similarity).
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[https://www.uniprot.org/uniprot/MATRX_LBV MATRX_LBV] Plays a major role in assembly and budding of virion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/2w2s_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w2/2w2s_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w2s ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2w2s" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lagos bat virus]]
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[[Category: Lagos bat lyssavirus]]
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[[Category: Assenberg, R]]
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[[Category: Large Structures]]
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[[Category: Bourhy, H]]
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[[Category: Assenberg R]]
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[[Category: Delmas, O]]
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[[Category: Bourhy H]]
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[[Category: Gholami, A]]
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[[Category: Delmas O]]
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[[Category: Graham, S C]]
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[[Category: Gholami A]]
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[[Category: Grimes, J M]]
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[[Category: Graham SC]]
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[[Category: Owens, R J]]
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[[Category: Grimes JM]]
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[[Category: Stuart, D I]]
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[[Category: Owens RJ]]
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[[Category: Talbi, C]]
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[[Category: Stuart DI]]
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[[Category: Verma, A]]
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[[Category: Talbi C]]
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[[Category: Matrix protein]]
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[[Category: Verma A]]
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[[Category: Polymer]]
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[[Category: Viral assembly]]
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[[Category: Viral morphogenesis]]
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[[Category: Viral protein]]
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[[Category: Vsv]]
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Current revision

Structure of the Lagos bat virus matrix protein

PDB ID 2w2s

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