4uxf

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'''Unreleased structure'''
 
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The entry 4uxf is ON HOLD until Paper Publication
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==Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, P21 native crystal==
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<StructureSection load='4uxf' size='340' side='right'caption='[[4uxf]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4uxf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UXF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UXF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uxf OCA], [https://pdbe.org/4uxf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uxf RCSB], [https://www.ebi.ac.uk/pdbsum/4uxf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uxf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FIBP_BPT4 FIBP_BPT4] Structural component of the proximal-half of the long-tail fiber. The long-tail fibers of T4 are about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves.<ref>PMID:8709154</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Long tail fibers of bacteriophage T4 are formed by proteins gp34, gp35, gp36, and gp37, with gp34 located at the phage-proximal end and gp37 at the phage-distal, receptor-binding end. We have solved the structure of the carboxy-terminal region of gp34, consisting of amino acids 894-1289, by single-wavelength anomalous diffraction and extended the structure to amino acids 744-1289 using data collected from crystals containing longer gp34-fragments. The structure reveals three repeats of a mixed alpha-beta fibrous domain in residues 744 to 877. A triple-helical neck connects to an extended triple beta-helix domain (amino acids 900-1127) punctuated by two beta-prism domains. Next, a beta-prism domain decorated with short helices and extended beta-helices is present (residues 1146-1238), while the C-terminal end is capped with another short beta-helical region and three beta-hairpins. The structure provides insight into the stability of the fibrous gp34 protein.
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Authors: Granell, M., Alvira, S., Garcia-Doval, C., Singh, A.K., van Raaij, M.J.
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Crystal Structure of the Carboxy-Terminal Region of the Bacteriophage T4 Proximal Long Tail Fiber Protein Gp34.,Granell M, Namura M, Alvira S, Kanamaru S, van Raaij MJ Viruses. 2017 Jun 30;9(7). pii: E168. doi: 10.3390/v9070168. PMID:28665339<ref>PMID:28665339</ref>
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Description: Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, P21 native crystal
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Granell, M]]
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<div class="pdbe-citations 4uxf" style="background-color:#fffaf0;"></div>
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[[Category: Garcia-Doval, C]]
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== References ==
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[[Category: Van Raaij, M.J]]
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<references/>
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[[Category: Alvira, S]]
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__TOC__
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[[Category: Singh, A.K]]
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</StructureSection>
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[[Category: Escherichia virus T4]]
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[[Category: Large Structures]]
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[[Category: Alvira S]]
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[[Category: Garcia-Doval C]]
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[[Category: Granell M]]
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[[Category: Singh AK]]
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[[Category: Van Raaij MJ]]

Current revision

Crystal structure of the carboxy-terminal region of the bacteriophage T4 proximal long tail fibre protein gp34, P21 native crystal

PDB ID 4uxf

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