1t6s

<StructureSection load='1t6s' size='340' side='right' caption='[[1t6s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>

<table><tr><td colspan='2'>[[1t6s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1T6S FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1t6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t6s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1t6s RCSB], [http://www.ebi.ac.uk/pdbsum/1t6s PDBsum], [http://www.topsan.org/Proteins/BSGC/1t6s TOPSAN]</span></td></tr>

[[http://www.uniprot.org/uniprot/Q8KF54_CHLTE Q8KF54_CHLTE]] Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity).

<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t6/1t6s_consurf.spt"</scriptWhenChecked>

</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].

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== Publication Abstract from PubMed ==

Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.

Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning.,Kim JS, Shin DH, Pufan R, Huang C, Yokota H, Kim R, Kim SH Proteins. 2006 Feb 1;62(2):322-8. PMID:16294331<ref>PMID:16294331</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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== References ==

<references/>

[[Category: Chlorobium tepidum tls]]

[[Category: Structural genomic]]

[[Category: Kim, J S]]

[[Category: Kim, R]]

[[Category: Kim, S H]]

[[Category: Shin, D H]]

[[Category: Unknown function]]