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3uou
From Proteopedia
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==Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase== | ==Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase== | ||
| - | <StructureSection load='3uou' size='340' side='right' caption='[[3uou]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='3uou' size='340' side='right'caption='[[3uou]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3uou]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3uou]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Stichodactyla_helianthus Stichodactyla helianthus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UOU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UOU FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uou FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uou OCA], [https://pdbe.org/3uou PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uou RCSB], [https://www.ebi.ac.uk/pdbsum/3uou PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uou ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/VKT1_STIHL VKT1_STIHL] Active against serine, cysteine, and aspartic proteases. Can bind vertebrate trypsin and chymotrypsin.<ref>PMID:22975140</ref> <ref>PMID:9027993</ref> |
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| + | ==See Also== | ||
| + | *[[Elastase 3D structures|Elastase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
[[Category: Stichodactyla helianthus]] | [[Category: Stichodactyla helianthus]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Betzel | + | [[Category: Betzel C]] |
| - | [[Category: Chavez | + | [[Category: Chavez MA]] |
| - | [[Category: Garcia-Fernandez | + | [[Category: Garcia-Fernandez R]] |
| - | [[Category: Gonzalez-Gonzalez | + | [[Category: Gonzalez-Gonzalez Y]] |
| - | [[Category: Perbandt | + | [[Category: Perbandt M]] |
| - | [[Category: Redecke | + | [[Category: Redecke L]] |
| - | [[Category: Rehders | + | [[Category: Rehders D]] |
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Current revision
Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase
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