4whf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of TR3 LBD in complex with 1-(3,4,5-trihydroxyphenyl)decan-1-one== | |
| - | + | <StructureSection load='4whf' size='340' side='right'caption='[[4whf]], [[Resolution|resolution]] 2.27Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4whf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WHF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3MX:1-(3,4,5-TRIHYDROXYPHENYL)DECAN-1-ONE'>3MX</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4whf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4whf OCA], [https://pdbe.org/4whf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4whf RCSB], [https://www.ebi.ac.uk/pdbsum/4whf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4whf ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref> |
| - | [[Category: Li | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cai QX]] | ||
| + | [[Category: Hou PP]] | ||
| + | [[Category: Li AZ]] | ||
| + | [[Category: Li FW]] | ||
| + | [[Category: Lin TW]] | ||
| + | [[Category: Tian XY]] | ||
| + | [[Category: Wang WJ]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Wu Q]] | ||
Current revision
Crystal Structure of TR3 LBD in complex with 1-(3,4,5-trihydroxyphenyl)decan-1-one
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Categories: Homo sapiens | Large Structures | Cai QX | Hou PP | Li AZ | Li FW | Lin TW | Tian XY | Wang WJ | Wang Y | Wu Q
