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4qr1

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==Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5==
==Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5==
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<StructureSection load='4qr1' size='340' side='right' caption='[[4qr1]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
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<StructureSection load='4qr1' size='340' side='right'caption='[[4qr1]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qr1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QR1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QR1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qr1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_M1 Streptococcus pyogenes serotype M1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QR1 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qr0|4qr0]], [[4qr2|4qr2]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.193&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qr1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qr1 RCSB], [http://www.ebi.ac.uk/pdbsum/4qr1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qr1 OCA], [https://pdbe.org/4qr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qr1 RCSB], [https://www.ebi.ac.uk/pdbsum/4qr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qr1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q99YS8_STRP1 Q99YS8_STRP1]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01471]
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[https://www.uniprot.org/uniprot/Q99YS8_STRP1 Q99YS8_STRP1] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01471]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4qr1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Endonuclease|Endonuclease]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bae, E]]
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[[Category: Large Structures]]
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[[Category: Ka, D]]
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[[Category: Streptococcus pyogenes serotype M1]]
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[[Category: Kim, D]]
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[[Category: Bae E]]
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[[Category: Deoxyribonuclease]]
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[[Category: Ka D]]
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[[Category: Ferredoxin-like fold]]
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[[Category: Kim D]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of Streptococcus pyogenes Cas2 at pH 6.5

PDB ID 4qr1

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