4tx0
From Proteopedia
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==The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-(2-methoxyethoxy)-3-(2-methoxyethyl)-3,10-diazabicyclo[4.3.1]decan-2-one== | ==The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-(2-methoxyethoxy)-3-(2-methoxyethyl)-3,10-diazabicyclo[4.3.1]decan-2-one== | ||
| - | <StructureSection load='4tx0' size='340' side='right' caption='[[4tx0]], [[Resolution|resolution]] 1.03Å' scene=''> | + | <StructureSection load='4tx0' size='340' side='right'caption='[[4tx0]], [[Resolution|resolution]] 1.03Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4tx0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TX0 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4tx0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TX0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TX0 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=384:(1S,5S,6R)-10-[(3,5-DICHLOROPHENYL)SULFONYL]-5-(2-METHOXYETHOXY)-3-(2-METHOXYETHYL)-3,10-DIAZABICYCLO[4.3.1]DECAN-2-ONE'>384</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.03Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=384:(1S,5S,6R)-10-[(3,5-DICHLOROPHENYL)SULFONYL]-5-(2-METHOXYETHOXY)-3-(2-METHOXYETHYL)-3,10-DIAZABICYCLO[4.3.1]DECAN-2-ONE'>384</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tx0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tx0 OCA], [https://pdbe.org/4tx0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tx0 RCSB], [https://www.ebi.ac.uk/pdbsum/4tx0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tx0 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4tx0" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[FKBP 3D structures|FKBP 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Bischoff | + | [[Category: Large Structures]] |
| - | [[Category: Bracher | + | [[Category: Bischoff M]] |
| - | [[Category: Hausch | + | [[Category: Bracher A]] |
| - | [[Category: Sippel | + | [[Category: Hausch F]] |
| - | + | [[Category: Sippel C]] | |
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Current revision
The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-(2-methoxyethoxy)-3-(2-methoxyethyl)-3,10-diazabicyclo[4.3.1]decan-2-one
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