2clz

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==MHC CLASS I NATURAL MUTANT H-2KBM8 HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND PBM1 PEPTIDE==
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<StructureSection load='2clz' size='340' side='right' caption='[[2clz]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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==Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and pBM1 peptide==
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<StructureSection load='2clz' size='340' side='right'caption='[[2clz]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2clz]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CLZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2clz]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CLZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CLZ FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a1m|1a1m]], [[1a1n|1a1n]], [[1a1o|1a1o]], [[1akj|1akj]], [[1b3j|1b3j]], [[1bd2|1bd2]], [[1bii|1bii]], [[1ce6|1ce6]], [[1ddh|1ddh]], [[1fo0|1fo0]], [[1fyt|1fyt]], [[1fzj|1fzj]], [[1fzk|1fzk]], [[1fzm|1fzm]], [[1fzo|1fzo]], [[1g7p|1g7p]], [[1g7q|1g7q]], [[1ha5|1ha5]], [[1hqr|1hqr]], [[1hxy|1hxy]], [[1icf|1icf]], [[1iie|1iie]], [[1im3|1im3]], [[1j8h|1j8h]], [[1je6|1je6]], [[1jwm|1jwm]], [[1jws|1jws]], [[1jwu|1jwu]], [[1k2d|1k2d]], [[1k8d|1k8d]], [[1kbg|1kbg]], [[1kg0|1kg0]], [[1kj2|1kj2]], [[1kj3|1kj3]], [[1kjm|1kjm]], [[1kjv|1kjv]], [[1kpu|1kpu]], [[1kpv|1kpv]], [[1ldp|1ldp]], [[1lo5|1lo5]], [[1mhc|1mhc]], [[1nam|1nam]], [[1osz|1osz]], [[1p1z|1p1z]], [[1qlf|1qlf]], [[1qo3|1qo3]], [[1rjy|1rjy]], [[1rjz|1rjz]], [[1rk0|1rk0]], [[1rk1|1rk1]], [[1seb|1seb]], [[1vac|1vac]], [[1vad|1vad]], [[1wbx|1wbx]], [[1wby|1wby]], [[1wbz|1wbz]], [[1yn6|1yn6]], [[1yn7|1yn7]], [[1zs8|1zs8]], [[2cii|2cii]], [[2clv|2clv]], [[2f74|2f74]], [[2fwo|2fwo]], [[2vaa|2vaa]], [[2vab|2vab]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2clz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2clz RCSB], [http://www.ebi.ac.uk/pdbsum/2clz PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2clz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2clz OCA], [https://pdbe.org/2clz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2clz RCSB], [https://www.ebi.ac.uk/pdbsum/2clz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2clz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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[https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/2clz_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cl/2clz_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2clz ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2clz" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[Major histocompatibility complex|Major histocompatibility complex]]
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*[[MHC 3D structures|MHC 3D structures]]
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*[[MHC I 3D structures|MHC I 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Auphan-Anezin, N]]
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[[Category: Auphan-Anezin N]]
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[[Category: Barrett-Wilt, G A]]
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[[Category: Barrett-Wilt GA]]
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[[Category: Guimezanes, A]]
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[[Category: Guimezanes A]]
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[[Category: Hunt, D F]]
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[[Category: Hunt DF]]
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[[Category: Malissen, B]]
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[[Category: Malissen B]]
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[[Category: Mazza, C]]
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[[Category: Mazza C]]
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[[Category: Montero-Julian, F]]
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[[Category: Montero-Julian F]]
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[[Category: Roussel, A]]
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[[Category: Roussel A]]
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[[Category: Schmitt-Verhulst, A M]]
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[[Category: Schmitt-Verhulst AM]]
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[[Category: Alloreactivity]]
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[[Category: Class i mhc]]
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[[Category: Glycoprotein]]
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[[Category: H-2kbm8]]
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[[Category: Immune response]]
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[[Category: Immune system]]
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[[Category: Immunoglobulin domain]]
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[[Category: Membrane]]
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[[Category: Mhc i]]
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[[Category: Transmembrane]]
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Current revision

Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and pBM1 peptide

PDB ID 2clz

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