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1w9i

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==MYOSIN II DICTYOSTELIUM DISCOIDEUM MOTOR DOMAIN S456Y BOUND WITH MGADP-BEFX==
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<StructureSection load='1w9i' size='340' side='right' caption='[[1w9i]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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==Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-BeFx==
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<StructureSection load='1w9i' size='340' side='right'caption='[[1w9i]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1w9i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1W9I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1w9i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W9I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1d0x|1d0x]], [[1d0y|1d0y]], [[1d0z|1d0z]], [[1d1a|1d1a]], [[1d1b|1d1b]], [[1d1c|1d1c]], [[1fmv|1fmv]], [[1fmw|1fmw]], [[1g8x|1g8x]], [[1jwy|1jwy]], [[1jx2|1jx2]], [[1lvk|1lvk]], [[1mma|1mma]], [[1mmd|1mmd]], [[1mmg|1mmg]], [[1mmn|1mmn]], [[1mnd|1mnd]], [[1mne|1mne]], [[1q5g|1q5g]], [[1vom|1vom]], [[1w9j|1w9j]], [[1w9k|1w9k]], [[1w9l|1w9l]], [[1yv3|1yv3]], [[2aka|2aka]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9i OCA], [https://pdbe.org/1w9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w9i RCSB], [https://www.ebi.ac.uk/pdbsum/1w9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w9i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1w9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1w9i RCSB], [http://www.ebi.ac.uk/pdbsum/1w9i PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/1w9i_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/1w9i_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w9i ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Myosin|Myosin]]
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*[[Myosin 3D Structures|Myosin 3D Structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
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[[Category: Myosin ATPase]]
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[[Category: Large Structures]]
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[[Category: Coureux, P D]]
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[[Category: Coureux P-D]]
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[[Category: Houdusse, A]]
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[[Category: Houdusse A]]
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[[Category: Morris, C A]]
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[[Category: Morris CA]]
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[[Category: Sweeney, H L]]
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[[Category: Sweeney HL]]
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[[Category: Wells, A L]]
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[[Category: Wells AL]]
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[[Category: Atpase]]
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[[Category: Molecular motor]]
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[[Category: Motor domain]]
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[[Category: Muscle contraction]]
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[[Category: Mutant]]
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[[Category: Myosin]]
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Current revision

Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-BeFx

PDB ID 1w9i

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