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4tvs

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==LAP1(aa356-583), H.sapiens, bound to VHH-BS1==
==LAP1(aa356-583), H.sapiens, bound to VHH-BS1==
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<StructureSection load='4tvs' size='340' side='right' caption='[[4tvs]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4tvs' size='340' side='right'caption='[[4tvs]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4tvs]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TVS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TVS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4tvs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TVS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tvs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tvs RCSB], [http://www.ebi.ac.uk/pdbsum/4tvs PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tvs OCA], [https://pdbe.org/4tvs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tvs RCSB], [https://www.ebi.ac.uk/pdbsum/4tvs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tvs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TOIP1_HUMAN TOIP1_HUMAN]] Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.<ref>PMID:23569223</ref>
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[https://www.uniprot.org/uniprot/TOIP1_HUMAN TOIP1_HUMAN] Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.<ref>PMID:23569223</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4tvs" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Schwartz, T U]]
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[[Category: Homo sapiens]]
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[[Category: Sosa, B A]]
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[[Category: Large Structures]]
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[[Category: Aaa+-associated]]
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[[Category: Vicugna pacos]]
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[[Category: Activator]]
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[[Category: Schwartz TU]]
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[[Category: Membrane protein]]
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[[Category: Sosa BA]]
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[[Category: Nuclear envelope protein]]
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Current revision

LAP1(aa356-583), H.sapiens, bound to VHH-BS1

PDB ID 4tvs

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