3sgi
From Proteopedia
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==Crystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosis== | ==Crystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosis== | ||
| - | <StructureSection load='3sgi' size='340' side='right' caption='[[3sgi]], [[Resolution|resolution]] 3.50Å' scene=''> | + | <StructureSection load='3sgi' size='340' side='right'caption='[[3sgi]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3sgi]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3sgi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SGI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sgi OCA], [https://pdbe.org/3sgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sgi RCSB], [https://www.ebi.ac.uk/pdbsum/3sgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sgi ProSAT]</span></td></tr> |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DNLJ_MYCTU DNLJ_MYCTU] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.[HAMAP-Rule:MF_01588] |
==See Also== | ==See Also== | ||
| - | *[[DNA ligase|DNA ligase]] | + | *[[DNA ligase 3D structures|DNA ligase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
| - | [[Category: Kukshal | + | [[Category: Kukshal V]] |
| - | [[Category: Ravishankar | + | [[Category: Ravishankar R]] |
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Current revision
Crystal structure of DNA ligase A BRCT domain deleted mutant of Mycobacterium tuberculosis
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