2a21

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[[Image:2a21.gif|left|200px]]
 
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{{Structure
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==Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+==
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|PDB= 2a21 |SIZE=350|CAPTION= <scene name='initialview01'>2a21</scene>, resolution 1.80&Aring;
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<StructureSection load='2a21' size='340' side='right'caption='[[2a21]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>
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<table><tr><td colspan='2'>[[2a21]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A21 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/3-deoxy-8-phosphooctulonate_synthase 3-deoxy-8-phosphooctulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.55 2.5.1.55]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= kdsA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 Aquifex aeolicus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a21 OCA], [https://pdbe.org/2a21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a21 RCSB], [https://www.ebi.ac.uk/pdbsum/2a21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a21 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KDSA_AQUAE KDSA_AQUAE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/2a21_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a21 ConSurf].
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<div style="clear:both"></div>
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'''Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+'''
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==See Also==
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*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2A21 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A21 OCA].
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[[Category: 3-deoxy-8-phosphooctulonate synthase]]
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[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Gatti, D L.]]
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[[Category: Gatti DL]]
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[[Category: Kona, F.]]
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[[Category: Kona F]]
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[[Category: Lu, J.]]
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[[Category: Lu J]]
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[[Category: Martin, P.]]
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[[Category: Martin P]]
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[[Category: Xu, X.]]
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[[Category: Xu X]]
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[[Category: PEP]]
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[[Category: PO4]]
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[[Category: ZN]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:44:25 2008''
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Current revision

Aquifex aeolicus KDO8PS in complex with PEP, PO4, and Zn2+

PDB ID 2a21

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