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3ier

From Proteopedia

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==Firefly luciferase apo structure (P41 form) with PEG 400 bound==
==Firefly luciferase apo structure (P41 form) with PEG 400 bound==
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<StructureSection load='3ier' size='340' side='right' caption='[[3ier]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='3ier' size='340' side='right'caption='[[3ier]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ier]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Photinus_pyralis Photinus pyralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IER OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IER FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ier]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Photinus_pyralis Photinus pyralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IER FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3iep|3iep]], [[3ies|3ies]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Photinus-luciferin_4-monooxygenase_(ATP-hydrolyzing) Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.12.7 1.13.12.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ier FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ier OCA], [https://pdbe.org/3ier PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ier RCSB], [https://www.ebi.ac.uk/pdbsum/3ier PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ier ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ier FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ier OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ier RCSB], [http://www.ebi.ac.uk/pdbsum/3ier PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LUCI_PHOPY LUCI_PHOPY]] Produces green light with a wavelength of 562 nm.
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[https://www.uniprot.org/uniprot/LUCI_PHOPY LUCI_PHOPY] Produces green light with a wavelength of 562 nm.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3ier_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3ier_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ier ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3ier" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Luciferase|Luciferase]]
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*[[Luciferase 3D structures|Luciferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Photinus pyralis]]
[[Category: Photinus pyralis]]
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[[Category: Auld, D S]]
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[[Category: Auld DS]]
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[[Category: Battaile, K P]]
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[[Category: Battaile KP]]
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[[Category: Hanzlik, R P]]
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[[Category: Hanzlik RP]]
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[[Category: Inglese, J]]
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[[Category: Inglese J]]
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[[Category: Lea, W A]]
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[[Category: Lea WA]]
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[[Category: Lovell, S]]
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[[Category: Lovell S]]
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[[Category: Maloney, D J]]
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[[Category: Maloney DJ]]
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[[Category: Raj, G]]
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[[Category: Raj G]]
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[[Category: Shen, M]]
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[[Category: Shen M]]
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[[Category: Simeonov, A]]
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[[Category: Simeonov A]]
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[[Category: Thomas, C J]]
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[[Category: Thomas CJ]]
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[[Category: Thorne, N]]
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[[Category: Thorne N]]
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[[Category: Atp-binding]]
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[[Category: Luminescence]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Monooxygenase]]
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[[Category: Nucleotide-binding]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxisome]]
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[[Category: Photoprotein]]
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Current revision

Firefly luciferase apo structure (P41 form) with PEG 400 bound

PDB ID 3ier

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