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2a9v

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[[Image:2a9v.gif|left|200px]]
 
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{{Structure
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==Crystal structure of a putative gmp synthase subunit a protein (ta0944m) from thermoplasma acidophilum at 2.45 A resolution==
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|PDB= 2a9v |SIZE=350|CAPTION= <scene name='initialview01'>2a9v</scene>, resolution 2.240&Aring;
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<StructureSection load='2a9v' size='340' side='right'caption='[[2a9v]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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<table><tr><td colspan='2'>[[2a9v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A9V FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/GMP_synthase_(glutamine-hydrolyzing) GMP synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.2 6.3.5.2]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.24&#8491;</td></tr>
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|GENE= guaAA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2303 Thermoplasma acidophilum])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a9v OCA], [https://pdbe.org/2a9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a9v RCSB], [https://www.ebi.ac.uk/pdbsum/2a9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a9v ProSAT], [https://www.topsan.org/Proteins/JCSG/2a9v TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUAAA_THEAC GUAAA_THEAC] Catalyzes the synthesis of GMP from XMP (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a9/2a9v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a9v ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of (np_394403.1) from THERMOPLASMA ACIDOPHILUM at 2.45 A resolution'''
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==See Also==
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*[[GMP synthase|GMP synthase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2A9V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A9V OCA].
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[[Category: Large Structures]]
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[[Category: GMP synthase (glutamine-hydrolyzing)]]
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[[Category: Single protein]]
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[[Category: Thermoplasma acidophilum]]
[[Category: Thermoplasma acidophilum]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
 
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[[Category: CL]]
 
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[[Category: GOL]]
 
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[[Category: SCN]]
 
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[[Category: jcsg]]
 
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[[Category: joint center for structural genomic]]
 
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[[Category: np_394403 1]]
 
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[[Category: protein structure initiative]]
 
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[[Category: psi]]
 
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[[Category: structural genomic]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:47:11 2008''
 

Current revision

Crystal structure of a putative gmp synthase subunit a protein (ta0944m) from thermoplasma acidophilum at 2.45 A resolution

PDB ID 2a9v

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