This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4e17
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin== | ==Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin== | ||
| - | <StructureSection load='4e17' size='340' side='right' caption='[[4e17]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='4e17' size='340' side='right'caption='[[4e17]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4e17]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4e17]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E17 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.304Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e17 OCA], [https://pdbe.org/4e17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e17 RCSB], [https://www.ebi.ac.uk/pdbsum/4e17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e17 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref> |
==See Also== | ==See Also== | ||
| + | *[[Catenin 3D structures|Catenin 3D structures]] | ||
*[[Vinculin|Vinculin]] | *[[Vinculin|Vinculin]] | ||
== References == | == References == | ||
| Line 17: | Line 18: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Bankston | + | [[Category: Bankston LA]] |
| - | [[Category: Cadwell | + | [[Category: Cadwell GW]] |
| - | [[Category: Choi | + | [[Category: Choi H-J]] |
| - | [[Category: Liddington | + | [[Category: Liddington RC]] |
| - | [[Category: Pokutta | + | [[Category: Pokutta S]] |
| - | [[Category: Weis | + | [[Category: Weis WI]] |
| - | + | ||
| - | + | ||
Current revision
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
| |||||||||||
