3vpo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:31, 8 November 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant==
==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant==
-
<StructureSection load='3vpo' size='340' side='right' caption='[[3vpo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+
<StructureSection load='3vpo' size='340' side='right'caption='[[3vpo]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3vpo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_caccae Bacteroides caccae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VPO FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3vpo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VPO FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3olj|3olj]], [[3vpm|3vpm]], [[3vpn|3vpn]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RR2, RRM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=47678 Bacteroides caccae])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vpo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpo OCA], [https://pdbe.org/3vpo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vpo RCSB], [https://www.ebi.ac.uk/pdbsum/3vpo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vpo ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vpo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vpo RCSB], [http://www.ebi.ac.uk/pdbsum/3vpo PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
+
[https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
==See Also==
==See Also==
-
*[[Ribonucleotide reductase|Ribonucleotide reductase]]
+
*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacteroides caccae]]
+
[[Category: Homo sapiens]]
-
[[Category: Ribonucleoside-diphosphate reductase]]
+
[[Category: Large Structures]]
-
[[Category: Chen, B]]
+
[[Category: Chen B]]
-
[[Category: Chen, X]]
+
[[Category: Chen X]]
-
[[Category: Liu, H]]
+
[[Category: Liu H]]
-
[[Category: Shao, J]]
+
[[Category: Shao J]]
-
[[Category: Xu, Z]]
+
[[Category: Xu Z]]
-
[[Category: Yang, C]]
+
[[Category: Yang C]]
-
[[Category: Zhang, L]]
+
[[Category: Zhang L]]
-
[[Category: Zhu, L]]
+
[[Category: Zhu L]]
-
[[Category: Zhu, W]]
+
[[Category: Zhu W]]
-
[[Category: Metal-binding]]
+
-
[[Category: Oxidoreductase]]
+

Current revision

Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant

PDB ID 3vpo

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools