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3wcy
From Proteopedia
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==Murine Ifnar1 in complex with interferon-beta== | ==Murine Ifnar1 in complex with interferon-beta== | ||
| - | <StructureSection load='3wcy' size='340' side='right' caption='[[3wcy]], [[Resolution|resolution]] 2.90Å' scene=''> | + | <StructureSection load='3wcy' size='340' side='right'caption='[[3wcy]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3wcy]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3wcy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WCY FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcy OCA], [https://pdbe.org/3wcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wcy RCSB], [https://www.ebi.ac.uk/pdbsum/3wcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wcy ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/INAR1_MOUSE INAR1_MOUSE] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. |
==See Also== | ==See Also== | ||
| - | *[[Interferon receptor|Interferon receptor]] | + | *[[Interferon 3D structures|Interferon 3D structures]] |
| + | *[[Interferon receptor 3D structures|Interferon receptor 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Hertzog | + | [[Category: Hertzog PJ]] |
| - | [[Category: Rossjohn | + | [[Category: Rossjohn J]] |
| - | [[Category: Vivian | + | [[Category: Vivian JP]] |
| - | [[Category: Weerd | + | [[Category: De Weerd NA]] |
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Current revision
Murine Ifnar1 in complex with interferon-beta
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