4bh9

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==A structural model of CAP mutant (T127L and S128I) in the apo state==
==A structural model of CAP mutant (T127L and S128I) in the apo state==
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<StructureSection load='4bh9' size='340' side='right' caption='[[4bh9]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='4bh9' size='340' side='right'caption='[[4bh9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4bh9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BH9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BH9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4bh9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BH9 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bhp|4bhp]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bh9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bh9 RCSB], [http://www.ebi.ac.uk/pdbsum/4bh9 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bh9 OCA], [https://pdbe.org/4bh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bh9 RCSB], [https://www.ebi.ac.uk/pdbsum/4bh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bh9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI]] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref>
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[https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 4bh9" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Catabolite gene activator protein|Catabolite gene activator protein]]
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*[[Catabolite gene activator protein 3D structures|Catabolite gene activator protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Kalodimos, C G]]
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[[Category: Large Structures]]
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[[Category: Tzeng, S R]]
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[[Category: Kalodimos CG]]
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[[Category: Transcription]]
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[[Category: Tzeng SR]]

Current revision

A structural model of CAP mutant (T127L and S128I) in the apo state

PDB ID 4bh9

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