4js9
From Proteopedia
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==Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme== | ==Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme== | ||
| - | <StructureSection load='4js9' size='340' side='right' caption='[[4js9]], [[Resolution|resolution]] 2.78Å' scene=''> | + | <StructureSection load='4js9' size='340' side='right'caption='[[4js9]], [[Resolution|resolution]] 2.78Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4js9]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4js9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JS9 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.784Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H4B:5,6,7,8-TETRAHYDROBIOPTERIN'>H4B</scene>, <scene name='pdbligand=MH0:MESOHEME'>MH0</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4js9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4js9 OCA], [https://pdbe.org/4js9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4js9 RCSB], [https://www.ebi.ac.uk/pdbsum/4js9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4js9 ProSAT]</span></td></tr> |
| - | < | + | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NOS2_MOUSE NOS2_MOUSE] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.<ref>PMID:16373578</ref> |
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| + | ==See Also== | ||
| + | *[[Nitric Oxide Synthase 3D structures|Nitric Oxide Synthase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bolisetty | + | [[Category: Mus musculus]] |
| - | [[Category: Hannibal | + | [[Category: Bolisetty K]] |
| - | [[Category: Misra | + | [[Category: Hannibal L]] |
| - | [[Category: Page | + | [[Category: Misra S]] |
| - | [[Category: Stuehr | + | [[Category: Page RC]] |
| - | [[Category: Yu | + | [[Category: Stuehr DJ]] |
| - | + | [[Category: Yu Z]] | |
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Current revision
Structural Characterization of Inducible Nitric Oxide Synthase Substituted With Mesoheme
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Categories: Large Structures | Mus musculus | Bolisetty K | Hannibal L | Misra S | Page RC | Stuehr DJ | Yu Z
