4m2z

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==Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE)==
==Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE)==
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<StructureSection load='4m2z' size='340' side='right' caption='[[4m2z]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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<StructureSection load='4m2z' size='340' side='right'caption='[[4m2z]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4m2z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M2Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4m2z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M2Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2nug|2nug]], [[4m30|4m30]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C5P:CYTIDINE-5-MONOPHOSPHATE'>C5P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aq_946, rnc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m2z OCA], [https://pdbe.org/4m2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m2z RCSB], [https://www.ebi.ac.uk/pdbsum/4m2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m2z ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_III Ribonuclease III], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.3 3.1.26.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m2z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m2z RCSB], [http://www.ebi.ac.uk/pdbsum/4m2z PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNC_AQUAE RNC_AQUAE]] Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.<ref>PMID:21138964</ref> <ref>PMID:16439209</ref>
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[https://www.uniprot.org/uniprot/RNC_AQUAE RNC_AQUAE] Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.<ref>PMID:21138964</ref> <ref>PMID:16439209</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4m2z" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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*[[Temp|Temp]]
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*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aquae]]
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Ribonuclease III]]
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[[Category: Large Structures]]
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[[Category: Gan, J]]
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[[Category: Synthetic construct]]
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[[Category: Ji, X]]
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[[Category: Gan J]]
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[[Category: Liang, Y H]]
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[[Category: Ji X]]
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[[Category: Shaw, G X]]
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[[Category: Liang Y-H]]
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[[Category: Tropea, J E]]
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[[Category: Shaw GX]]
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[[Category: Waugh, D S]]
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[[Category: Tropea JE]]
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[[Category: Dsrna]]
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[[Category: Waugh DS]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-rna complex]]
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[[Category: Rna binding]]
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[[Category: Rna processing]]
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[[Category: Rnase iii]]
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Current revision

Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE)

PDB ID 4m2z

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