2b21

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[[Image:2b21.gif|left|200px]]
 
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{{Structure
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==RADA Recombinase in complex with AMPPNP at pH 6.0==
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|PDB= 2b21 |SIZE=350|CAPTION= <scene name='initialview01'>2b21</scene>, resolution 2.4&Aring;
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<StructureSection load='2b21' size='340' side='right'caption='[[2b21]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene> and <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER'>ANP</scene>
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<table><tr><td colspan='2'>[[2b21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B21 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE= radA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 Methanococcus voltae])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b21 OCA], [https://pdbe.org/2b21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b21 RCSB], [https://www.ebi.ac.uk/pdbsum/2b21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b21 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RADA_METVO RADA_METVO] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/2b21_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b21 ConSurf].
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<div style="clear:both"></div>
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'''RADA Recombinase in complex with AMPPNP at pH 6.0'''
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==See Also==
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*[[Resolvase 3D structures|Resolvase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2B21 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B21 OCA].
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[[Category: Large Structures]]
[[Category: Methanococcus voltae]]
[[Category: Methanococcus voltae]]
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[[Category: Single protein]]
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[[Category: He Y]]
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[[Category: He, Y.]]
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[[Category: Luo Y]]
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[[Category: Luo, Y.]]
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[[Category: Qian X]]
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[[Category: Qian, X.]]
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[[Category: Wu Y]]
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[[Category: Wu, Y.]]
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[[Category: ANP]]
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[[Category: K]]
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[[Category: MG]]
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[[Category: atpase]]
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[[Category: co-factor]]
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[[Category: ph-dependence]]
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[[Category: protein-atp complex]]
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[[Category: rada/adp complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:56:38 2008''
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Current revision

RADA Recombinase in complex with AMPPNP at pH 6.0

PDB ID 2b21

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OCA

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