3qqn

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==The retinal specific CD147 Ig0 domain: from molecular structure to biological activity==
==The retinal specific CD147 Ig0 domain: from molecular structure to biological activity==
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<StructureSection load='3qqn' size='340' side='right' caption='[[3qqn]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
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<StructureSection load='3qqn' size='340' side='right'caption='[[3qqn]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qqn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QQN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qqn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QQN FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.309&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qr2|3qr2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSG, UNQ6505/PRO21383 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qqn OCA], [https://pdbe.org/3qqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qqn RCSB], [https://www.ebi.ac.uk/pdbsum/3qqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qqn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qqn RCSB], [http://www.ebi.ac.uk/pdbsum/3qqn PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/BASI_HUMAN BASI_HUMAN]] Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.<ref>PMID:17127621</ref>
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3qqn" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[3D structures of basigin|3D structures of basigin]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Armstrong, G S]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Armstrong GS]]
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[[Category: Eisenmesser, E Z]]
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[[Category: Eisenmesser EZ]]
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[[Category: Isern, N G]]
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[[Category: Isern NG]]
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[[Category: Kieft, J S]]
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[[Category: Kieft JS]]
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[[Category: Redzic, J S]]
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[[Category: Redzic JS]]
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[[Category: Beta sheet]]
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[[Category: Bsgc]]
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[[Category: Cd147]]
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[[Category: Cell adhesion]]
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[[Category: Emmprin]]
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[[Category: Immunoglobulin-like domain]]
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The retinal specific CD147 Ig0 domain: from molecular structure to biological activity

PDB ID 3qqn

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