4j9j

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==Structure of designed HisF==
==Structure of designed HisF==
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<StructureSection load='4j9j' size='340' side='right' caption='[[4j9j]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='4j9j' size='340' side='right'caption='[[4j9j]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4j9j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J9J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4j9j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J9J FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hisF, TM_1036 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243274 Thermotoga maritima MSB8])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j9j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j9j RCSB], [http://www.ebi.ac.uk/pdbsum/4j9j PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j9j OCA], [https://pdbe.org/4j9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j9j RCSB], [https://www.ebi.ac.uk/pdbsum/4j9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j9j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA]] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013]
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[https://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4j9j" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[IGPS 3D structures|IGPS 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thermotoga maritima msb8]]
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[[Category: Large Structures]]
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[[Category: Rajendran, C]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Sperl, J]]
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[[Category: Rajendran C]]
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[[Category: Sterner, R]]
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[[Category: Sperl J]]
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[[Category: Beta barrel]]
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[[Category: Sterner R]]
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[[Category: Lyase]]
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[[Category: Protein engineering]]
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Current revision

Structure of designed HisF

PDB ID 4j9j

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