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3mc2

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==Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase==
==Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase==
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<StructureSection load='3mc2' size='340' side='right' caption='[[3mc2]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='3mc2' size='340' side='right'caption='[[3mc2]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3mc2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MC2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3mc2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MC2 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">1300017J02Rik, mICA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">1300017J02Rik, mICA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mc2 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc2 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc2 OCA], [https://pdbe.org/3mc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mc2 RCSB], [https://www.ebi.ac.uk/pdbsum/3mc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q9DBD0_MOUSE Q9DBD0_MOUSE]] Inhibitor for carbonic anhydrase 2 (CA2). Does not bind iron ions.<ref>PMID:17511619</ref> <ref>PMID:18712936</ref>
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[[https://www.uniprot.org/uniprot/ICA_MOUSE ICA_MOUSE]] Inhibitor for carbonic anhydrase 2 (CA2). Does not bind iron ions.<ref>PMID:17511619</ref> <ref>PMID:18712936</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/3mc2_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mc/3mc2_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mc2 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3mc2" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Mus musculus]]
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[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
[[Category: Eckenroth, B E]]
[[Category: Eckenroth, B E]]
[[Category: Everse, S J]]
[[Category: Everse, S J]]

Current revision

Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase

PDB ID 3mc2

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