3qte

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==Crystal structure of human alpha-defensin 6 (H27W mutant)==
==Crystal structure of human alpha-defensin 6 (H27W mutant)==
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<StructureSection load='3qte' size='340' side='right' caption='[[3qte]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='3qte' size='340' side='right'caption='[[3qte]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qte]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QTE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QTE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qte]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QTE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QTE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.949&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zmq|1zmq]], [[1zmp|1zmp]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qte OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qte RCSB], [http://www.ebi.ac.uk/pdbsum/3qte PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qte FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qte OCA], [https://pdbe.org/3qte PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qte RCSB], [https://www.ebi.ac.uk/pdbsum/3qte PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qte ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DEF6_HUMAN DEF6_HUMAN]] Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1.<ref>PMID:15616305</ref> <ref>PMID:17088326</ref>
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[https://www.uniprot.org/uniprot/DEF6_HUMAN DEF6_HUMAN] Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1.<ref>PMID:15616305</ref> <ref>PMID:17088326</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3qte" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Defensin|Defensin]]
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*[[Defensin 3D structures|Defensin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lu, W]]
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[[Category: Homo sapiens]]
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[[Category: Pazgier, M]]
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[[Category: Large Structures]]
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[[Category: Antimicrobial protein]]
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[[Category: Lu W]]
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[[Category: Hd6]]
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[[Category: Pazgier M]]
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[[Category: Human alpha defensin]]
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[[Category: Paneth cells defensin]]
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Current revision

Crystal structure of human alpha-defensin 6 (H27W mutant)

PDB ID 3qte

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