4bqc

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==Crystal structure of the FN5 and FN6 domains of NEO1 bound to SOS==
==Crystal structure of the FN5 and FN6 domains of NEO1 bound to SOS==
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<StructureSection load='4bqc' size='340' side='right' caption='[[4bqc]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='4bqc' size='340' side='right'caption='[[4bqc]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4bqc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BQC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4bqc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BQC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SCR:SUCROSE+OCTASULFATE'>SCR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bq6|4bq6]], [[4bq7|4bq7]], [[4bq8|4bq8]], [[4bq9|4bq9]], [[4bqb|4bqb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=YYJ:1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose'>YYJ</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bqc RCSB], [http://www.ebi.ac.uk/pdbsum/4bqc PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqc OCA], [https://pdbe.org/4bqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bqc RCSB], [https://www.ebi.ac.uk/pdbsum/4bqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bqc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NEO1_MOUSE NEO1_MOUSE]] May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues.
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[https://www.uniprot.org/uniprot/NEO1_MOUSE NEO1_MOUSE] May be involved as a regulatory protein in the transition of undifferentiated proliferating cells to their differentiated state. May also function as a cell adhesion molecule in a broad spectrum of embryonic and adult tissues.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4bqc" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Aricescu, A R]]
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[[Category: Aricescu AR]]
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[[Category: Bell, C H]]
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[[Category: Bell CH]]
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[[Category: Bishop, B]]
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[[Category: Bishop B]]
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[[Category: Gilbert, R J.C]]
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[[Category: Gilbert RJC]]
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[[Category: Healey, E]]
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[[Category: Healey E]]
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[[Category: Pasterkamp, R J]]
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[[Category: Pasterkamp RJ]]
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[[Category: Siebold, C]]
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[[Category: Siebold C]]
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[[Category: Tang, C]]
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[[Category: Tang C]]
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[[Category: VanErp, S]]
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[[Category: VanErp S]]
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[[Category: Cell adhesion]]
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Current revision

Crystal structure of the FN5 and FN6 domains of NEO1 bound to SOS

PDB ID 4bqc

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