This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2xqz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:02, 23 August 2023) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
==NEUTRON STRUCTURE OF THE PERDEUTERATED TOHO-1 R274N R276N DOUBLE MUTANT BETA-LACTAMASE==
+
 
-
<StructureSection load='2xqz' size='340' side='right' caption='[[2xqz]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
==Neutron structure of the perdeuterated Toho-1 R274N R276N double mutant beta-lactamase==
 +
<StructureSection load='2xqz' size='340' side='right'caption='[[2xqz]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2xqz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XQZ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2xqz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQZ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Neutron Diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1iyp|1iyp]], [[1we4|1we4]], [[2wyx|2wyx]], [[1iys|1iys]], [[1iyo|1iyo]], [[2xr0|2xr0]], [[1bza|1bza]], [[1iyq|1iyq]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xqz OCA], [https://pdbe.org/2xqz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xqz RCSB], [https://www.ebi.ac.uk/pdbsum/2xqz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xqz ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xqz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xqz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xqz RCSB], [http://www.ebi.ac.uk/pdbsum/2xqz PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX]] Has strong cefotaxime-hydrolyzing activity.
+
[https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2xqz" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Beta-lactamase|Beta-lactamase]]
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Beta-lactamase]]
 
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Blakeley, M P]]
+
[[Category: Large Structures]]
-
[[Category: Chen, Y]]
+
[[Category: Blakeley MP]]
-
[[Category: Coates, L]]
+
[[Category: Chen Y]]
-
[[Category: Cooper, J]]
+
[[Category: Coates L]]
-
[[Category: Tomanicek, S J]]
+
[[Category: Cooper J]]
-
[[Category: Wang, K K]]
+
[[Category: Tomanicek SJ]]
-
[[Category: Weiss, K L]]
+
[[Category: Wang KK]]
-
[[Category: Ctx-m-type esbl]]
+
[[Category: Weiss KL]]
-
[[Category: Hydrolase]]
+

Current revision

Neutron structure of the perdeuterated Toho-1 R274N R276N double mutant beta-lactamase

PDB ID 2xqz

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools