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3g01

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==Structure of GrC mutant E192R/E193G==
==Structure of GrC mutant E192R/E193G==
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<StructureSection load='3g01' size='340' side='right' caption='[[3g01]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='3g01' size='340' side='right'caption='[[3g01]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3g01]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G01 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3g01]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G01 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fzz|3fzz]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g01 RCSB], [http://www.ebi.ac.uk/pdbsum/3g01 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g01 OCA], [https://pdbe.org/3g01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g01 RCSB], [https://www.ebi.ac.uk/pdbsum/3g01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g01 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GRAC_MOUSE GRAC_MOUSE]] This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.
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[https://www.uniprot.org/uniprot/GRAC_MOUSE GRAC_MOUSE] This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/3g01_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/3g01_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g01 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3g01" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Buckle, A M]]
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[[Category: Buckle AM]]
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[[Category: Kaiserman, D]]
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[[Category: Kaiserman D]]
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[[Category: Whisstock, J C]]
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[[Category: Whisstock JC]]
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[[Category: Cytolysis]]
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[[Category: Hydrolase]]
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[[Category: Protease]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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Current revision

Structure of GrC mutant E192R/E193G

PDB ID 3g01

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