2bpu

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[[Image:2bpu.gif|left|200px]]
 
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{{Structure
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==The Kedge Holmium Derivative of Hen Egg-White Lysozyme at high resolution from Single Wavelength Anomalous Diffraction==
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|PDB= 2bpu |SIZE=350|CAPTION= <scene name='initialview01'>2bpu</scene>, resolution 1.35&Aring;
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<StructureSection load='2bpu' size='340' side='right'caption='[[2bpu]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Ho+Binding+Site+For+Chain+A'>AC1</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=HO:HOLMIUM ATOM'>HO</scene>
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<table><tr><td colspan='2'>[[2bpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BPU FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HO:HOLMIUM+ATOM'>HO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bpu OCA], [https://pdbe.org/2bpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bpu RCSB], [https://www.ebi.ac.uk/pdbsum/2bpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bpu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/2bpu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bpu ConSurf].
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<div style="clear:both"></div>
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'''THE KEDGE HOLMIUM DERIVATIVE OF HEN EGG-WHITE LYSOZYME AT HIGH RESOLUTION FROM SINGLE WAVELENGTH ANOMALOUS DIFFRACTION'''
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==See Also==
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*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2BPU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BPU OCA].
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__TOC__
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Lysozyme]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Di Michiel M]]
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[[Category: Honkimaki, V.]]
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[[Category: Honkimaki V]]
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[[Category: Jakoncic, J.]]
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[[Category: Jakoncic J]]
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[[Category: Jouanneau, Y.]]
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[[Category: Jouanneau Y]]
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[[Category: Michiel, M Di.]]
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[[Category: Stojanoff V]]
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[[Category: Stojanoff, V.]]
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[[Category: Zhong Z]]
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[[Category: Zhong, Z.]]
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[[Category: CL]]
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[[Category: HO]]
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[[Category: NA]]
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[[Category: allergen]]
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[[Category: compton]]
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[[Category: experimental phase]]
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[[Category: glycosidase]]
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[[Category: high resolution]]
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[[Category: holmium]]
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[[Category: hydrolase bacteriolytic enzyme]]
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[[Category: kedge]]
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[[Category: sad]]
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[[Category: ultra high energy]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:05:05 2008''
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Current revision

The Kedge Holmium Derivative of Hen Egg-White Lysozyme at high resolution from Single Wavelength Anomalous Diffraction

PDB ID 2bpu

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