1t90
From Proteopedia
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==Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis== | ==Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis== | ||
| - | <StructureSection load='1t90' size='340' side='right' caption='[[1t90]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='1t90' size='340' side='right'caption='[[1t90]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1t90]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1t90]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T90 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t90 OCA], [https://pdbe.org/1t90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t90 RCSB], [https://www.ebi.ac.uk/pdbsum/1t90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t90 ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/IOLA_BACSU IOLA_BACSU] Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.<ref>PMID:16332250</ref> <ref>PMID:18310071</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t9/1t90_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t9/1t90_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t90 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
| - | [[Category: Aubry | + | [[Category: Large Structures]] |
| - | [[Category: Branlant | + | [[Category: Aubry A]] |
| - | [[Category: Corbier | + | [[Category: Branlant G]] |
| - | [[Category: Didierjean | + | [[Category: Corbier C]] |
| - | [[Category: Dubourg | + | [[Category: Didierjean C]] |
| - | [[Category: Stines-Chaumeil | + | [[Category: Dubourg H]] |
| - | [[Category: Talfournier | + | [[Category: Stines-Chaumeil C]] |
| - | + | [[Category: Talfournier F]] | |
| - | + | ||
Current revision
Crystal structure of methylmalonate semialdehyde dehydrogenase from Bacillus subtilis
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