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2eu1
From Proteopedia
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==Crystal structure of the chaperonin GroEL-E461K== | ==Crystal structure of the chaperonin GroEL-E461K== | ||
| - | <StructureSection load='2eu1' size='340' side='right' caption='[[2eu1]], [[Resolution|resolution]] 3.29Å' scene=''> | + | <StructureSection load='2eu1' size='340' side='right'caption='[[2eu1]], [[Resolution|resolution]] 3.29Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2eu1]] is a 14 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2eu1]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EU1 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.29Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eu1 OCA], [https://pdbe.org/2eu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eu1 RCSB], [https://www.ebi.ac.uk/pdbsum/2eu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eu1 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/2eu1_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/2eu1_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eu1 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2eu1" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] | |
| - | *[[Heat Shock | + | |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Agirre | + | [[Category: Large Structures]] |
| - | [[Category: Cabo-Bilbao | + | [[Category: Agirre J]] |
| - | [[Category: Guerin | + | [[Category: Cabo-Bilbao A]] |
| - | [[Category: Mechaly | + | [[Category: Guerin DMA]] |
| - | [[Category: Muga | + | [[Category: Mechaly AE]] |
| - | [[Category: Sot | + | [[Category: Muga A]] |
| - | [[Category: Spinelli | + | [[Category: Sot B]] |
| - | + | [[Category: Spinelli S]] | |
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Current revision
Crystal structure of the chaperonin GroEL-E461K
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Categories: Escherichia coli | Large Structures | Agirre J | Cabo-Bilbao A | Guerin DMA | Mechaly AE | Muga A | Sot B | Spinelli S
