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4gvs

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==X-ray structure of the Archaeoglobus fulgidus methenyl-tetrahydromethanopterin cyclohydrolase in complex with N5-formyl-tetrahydromethanopterin==
==X-ray structure of the Archaeoglobus fulgidus methenyl-tetrahydromethanopterin cyclohydrolase in complex with N5-formyl-tetrahydromethanopterin==
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<StructureSection load='4gvs' size='340' side='right' caption='[[4gvs]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4gvs' size='340' side='right'caption='[[4gvs]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gvs]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GVS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GVS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gvs]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GVS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F4M:1-[4-({(1R)-1-[(6S,7R)-2-AMINO-5-FORMYL-7-METHYL-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]ETHYL}AMINO)PHENYL]-1-DEOXY-5-O-{5-O-[(R)-{[(1R)-1,3-DICARBOXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]-ALPHA-D-RIBOFURANOSYL}-D-RIBITOL'>F4M</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gvq|4gvq]], [[4gvr|4gvr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F4M:1-[4-({(1R)-1-[(6S,7R)-2-amino-5-formyl-7-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]ethyl}amino)phenyl]-1-deoxy-5+-O-{5-O-[(R)-{[(1R)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol'>F4M</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AF_1935, mch ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gvs OCA], [https://pdbe.org/4gvs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gvs RCSB], [https://www.ebi.ac.uk/pdbsum/4gvs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gvs ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methenyltetrahydromethanopterin_cyclohydrolase Methenyltetrahydromethanopterin cyclohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.27 3.5.4.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gvs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gvs RCSB], [http://www.ebi.ac.uk/pdbsum/4gvs PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MCH_ARCFU MCH_ARCFU]] Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
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[https://www.uniprot.org/uniprot/MCH_ARCFU MCH_ARCFU] Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4gvs" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Cyclohydrolase|Cyclohydrolase]]
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*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arcfu]]
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[[Category: Archaeoglobus fulgidus DSM 4304]]
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[[Category: Methenyltetrahydromethanopterin cyclohydrolase]]
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[[Category: Large Structures]]
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[[Category: Demmer, U]]
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[[Category: Demmer U]]
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[[Category: Ermler, U]]
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[[Category: Ermler U]]
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[[Category: Moll, J]]
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[[Category: Moll J]]
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[[Category: Shima, S]]
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[[Category: Shima S]]
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[[Category: Upadhyay, V]]
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[[Category: Upadhyay V]]
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[[Category: Warkentin, E]]
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[[Category: Warkentin E]]
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[[Category: Hydrolase]]
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[[Category: N5-formyl-tetrahydromethanopterin]]
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Current revision

X-ray structure of the Archaeoglobus fulgidus methenyl-tetrahydromethanopterin cyclohydrolase in complex with N5-formyl-tetrahydromethanopterin

PDB ID 4gvs

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