3w45

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==Crystal structure of RsbX in complex with cobalt in space group P1==
==Crystal structure of RsbX in complex with cobalt in space group P1==
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<StructureSection load='3w45' size='340' side='right' caption='[[3w45]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='3w45' size='340' side='right'caption='[[3w45]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3w45]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W45 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W45 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3w45]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W45 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3w40|3w40]], [[3w41|3w41]], [[3w42|3w42]], [[3w43|3w43]], [[3w44|3w44]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU04740, rsbX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w45 OCA], [https://pdbe.org/3w45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w45 RCSB], [https://www.ebi.ac.uk/pdbsum/3w45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w45 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoserine_phosphatase Phosphoserine phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.3 3.1.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w45 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w45 RCSB], [http://www.ebi.ac.uk/pdbsum/3w45 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RSBX_BACSU RSBX_BACSU]] Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels.<ref>PMID:1592822</ref> <ref>PMID:8468294</ref> <ref>PMID:8824586</ref> <ref>PMID:9658013</ref>
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[https://www.uniprot.org/uniprot/RSBX_BACSU RSBX_BACSU] Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels.<ref>PMID:1592822</ref> <ref>PMID:8468294</ref> <ref>PMID:8824586</ref> <ref>PMID:9658013</ref>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsu]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
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[[Category: Phosphoserine phosphatase]]
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[[Category: Large Structures]]
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[[Category: Baba, S]]
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[[Category: Baba S]]
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[[Category: Kumasaka, T]]
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[[Category: Kumasaka T]]
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[[Category: Makino, M]]
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[[Category: Makino M]]
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[[Category: Shimizu, N]]
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[[Category: Shimizu N]]
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[[Category: Teh, A H]]
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[[Category: Teh AH]]
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[[Category: Yamamoto, M]]
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[[Category: Yamamoto M]]
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[[Category: Alpha-beta beta-alpha sandwich fold]]
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[[Category: Dephosphorylation]]
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[[Category: Environmental stress]]
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[[Category: Gene expression regulation]]
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[[Category: Hydrolase]]
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[[Category: Magnesium/manganese binding]]
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[[Category: Phosphatase]]
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[[Category: Phosphoric monoester hydrolase]]
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[[Category: Protein phosphatase]]
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[[Category: Signaling protein]]
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[[Category: Stressosome]]
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[[Category: Tertiary]]
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Current revision

Crystal structure of RsbX in complex with cobalt in space group P1

PDB ID 3w45

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