2xva
From Proteopedia
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==Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin== | ==Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin== | ||
| - | <StructureSection load='2xva' size='340' side='right' caption='[[2xva]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='2xva' size='340' side='right'caption='[[2xva]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xva]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._MG1655 Escherichia coli str. K-12 substr. MG1655]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XVA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xva OCA], [https://pdbe.org/2xva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xva RCSB], [https://www.ebi.ac.uk/pdbsum/2xva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xva ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TEHB_ECOLI TEHB_ECOLI] S-adenosyl-L-methionine dependent methyltransferase that catalyzes the methylation of tellurite and is responsible for tellurite resistance when present in high copy number. Can also methylate selenite and selenium dioxide. Is thus able to detoxify different chalcogens. Can not methylate arsenic compounds.<ref>PMID:11053398</ref> <ref>PMID:21244361</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2xva" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Escherichia coli]] | + | [[Category: Escherichia coli str. K-12 substr. MG1655]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Beis K]] |
| - | [[Category: | + | [[Category: Cameron AD]] |
| - | [[Category: | + | [[Category: Choudhury HG]] |
| - | [[Category: | + | [[Category: Iwata S]] |
Current revision
Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin
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