This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1l4t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:47, 29 November 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==SOLUTION NMR STRUCTURE OF THE CCK2E3==
==SOLUTION NMR STRUCTURE OF THE CCK2E3==
-
<StructureSection load='1l4t' size='340' side='right' caption='[[1l4t]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
+
<StructureSection load='1l4t' size='340' side='right'caption='[[1l4t]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1l4t]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L4T FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1l4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L4T FirstGlance]. <br>
-
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l4t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l4t RCSB], [http://www.ebi.ac.uk/pdbsum/1l4t PDBsum]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l4t OCA], [https://pdbe.org/1l4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l4t RCSB], [https://www.ebi.ac.uk/pdbsum/1l4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l4t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/GASR_HUMAN GASR_HUMAN]] Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.<ref>PMID:8349705</ref> <ref>PMID:8185170</ref> <ref>PMID:7848914</ref> <ref>PMID:10913157</ref> <ref>PMID:11495676</ref> <ref>PMID:8221657</ref> Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.<ref>PMID:8349705</ref> <ref>PMID:8185170</ref> <ref>PMID:7848914</ref> <ref>PMID:10913157</ref> <ref>PMID:11495676</ref> <ref>PMID:8221657</ref>
+
[https://www.uniprot.org/uniprot/GASR_HUMAN GASR_HUMAN] Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.<ref>PMID:8349705</ref> <ref>PMID:8185170</ref> <ref>PMID:7848914</ref> <ref>PMID:10913157</ref> <ref>PMID:11495676</ref> <ref>PMID:8221657</ref> Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.<ref>PMID:8349705</ref> <ref>PMID:8185170</ref> <ref>PMID:7848914</ref> <ref>PMID:10913157</ref> <ref>PMID:11495676</ref> <ref>PMID:8221657</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 1l4t" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Giragossian, C]]
+
[[Category: Homo sapiens]]
-
[[Category: Mierke, D F]]
+
[[Category: Large Structures]]
-
[[Category: Hormone-growth factor receptor complex]]
+
[[Category: Giragossian C]]
-
[[Category: Hormone/growth factor receptor]]
+
[[Category: Mierke DF]]

Current revision

SOLUTION NMR STRUCTURE OF THE CCK2E3

PDB ID 1l4t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1l4t"
Personal tools